Review article (Published On: 12-Mar-2021)

Pathophysiology of rotavirus in calves and zoonotic importance

umer seid geletu and Munera Ahmednur Usmael

J. Vet. Res. Adv., 03 (01):01-24

umer seid geletu: Oda Bultum University

Munera Ahmednur Usmael: West Haraghe zone Livestock and Fisher office

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Article History: Received on: 28-Oct-20, Accepted on: 01-Mar-21, Published on: 12-Mar-21

Corresponding Author: umer seid geletu


Citation: Seid U and Ahmednur M (2021). Pathophysiology of rotavirus in calves and zoonotic importance. J. Vet. Res. Adv., 03 (01):01-24


Rotavirus is a major pathogen responsible for diarrheal disease in calves resulting in loss of productivity and economy of farmers. However, various facets of diarrheal disease caused by rotavirus in calves in world are inadequately understood. Considering that diarrheal disease caused by rotavirus is a vital health problem in calves that interrupts production benefits with reduced weight gain and increased mortality, and it’s potential for zoonotic spread. The pathological changes that made by rotavirus are almost exclusively limited to the small intestine that leads diarrhea. It is environmentally distributed worldwide and was extensively studied. Re-assortment is one of the important mechanisms for generating genetic diversity of rotaviruses and eventually for viral evolution. So, primary strategy to reduce the burden of rotavirus infections by practicing early colostrum’s feeding in newborn calves, using vaccine, and improving livestock management. Therefore, this review was made to get overview epidemiology status and zoonotic importance of bovine rotavirus.


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