Abstract

Aim: Purpose of the study was to evaluate the influence of lidocaine and bupivacaine spinal anaesthesia on some physiological parameters in dogs.

Method and materials:  Six male dogs were used for the study. The dogs were allowed to acclimatised for two weeks with food and water been provided ad-libitum. After aseptic preparation, the dogs were divided into two groups of three dogs each. Both groups were sedated with xylazine at 2mg/kg and group one was anaesthetised using spinal anaesthesia with lidocaine and group two using bupivacaine spinal anaesthesia. The animals were draped and open castration performed. Vitals parameters and blood samples were taken and documented. Data analyzed statistically, with p-values <0.05 considered statistically significant.

Results: Lidocaine group observed approximately 89 % drop while bupivacaine recorded 92% sharp drop-in respiratory rate five minutes after xylazine and spinal anaesthesia. Furthermore, bupivacaine showed prolonged respiratory rate suppression relative to lidocaine group. The comparative analysis of the pulse rate of dogs, treated with lidocaine and bupivacaine, showed similar fluctuations. Five minutes into the surgery, the lidocaine group had a mean temperature of 38.17±3.58, while the bupivacaine group was slightly higher at 39.17±1.06. After surgery, the temperature in the lidocaine group was significantly higher compared to the bupivacaine group. Most blood parameters were statistically unaffected, however, statistical significance were seen in white blood cell count and neutrophil count.

Conclusion: It was concluded that Spinal anaesthesia with lidocaine has short effect on body temperature and less stimulation on white blood cells unlike bupivacaine. Hence, with patients with cardiovascular conditions should be given bupivacaine spinal anaesthesia with cautions.

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